Can you further explain the science behind how Valerian root works in the body to produce its anxiety-reducing and sleep-enhancing effects? References: Kasper, S., Gastpar, M., Müller, W., Volz, H., Möller, H., Dienel, A., & Schlafke, S. (2015). Silexan in anxiety disorders: Clinical data and pharmacological background. Wiener medizinische Wochenschrift (1946), 165(13-14), 263–272. Mayo Clinic. (2022). Anxiety disorders. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/anxiety/symptoms-causes/syc-20350961. Salvemini, I., Bersinger, N., & Payne, B. (2015). A systematic review of the literature on disorders of sleep and wakefulness in Parkinson's disease from 2005 to 2015. Sleep medicine reviews, 35, 33-50.

The Role of Valerian Root in Reducing Anxiety and Promoting Sleep

Valerian root is a herbal supplement well-regarded for its sedative and anxiolytic effects, and is historically used in traditional medicine to ease sleep disorders and anxiety symptoms. The root extract of the Valeriana officinalis plant appears to interact with the neurotransmitter gamma-aminobutyric acid (GABA) in the brain. GABA controls nerve impulses in your nervous system, providing a calming effect when levels are healthy. In fact, many prescription drugs for anxiety, such as Benzodiazepines, work by increasing GABA activity in the brain.

Valerian Root and GABA Mechanism

It is believed that certain compounds in Valerian Root, like valerenic acid, can inhibit the breakdown of GABA in the brain, resulting in feelings of tranquillity and peace. This mechanism might be responsible for the sleep-enhancing effects of Valerian Root, as GABA also plays a critical role in our sleep cycles. Furthermore, given that low GABA levels have been linked to acute and chronic stress, anxiety, and low-quality, disrupted sleep, maintaining healthy GABA levels can help ameliorate these conditions.

Effects on Anxiety and Sleep Quality

Clinical studies have shown promising results in the utilization of Valerian Root for anxiety and sleep disorders. In a double-blind study by Kasper et al., (2015) patients treated with Silexan, a proprietary blend of lavender oil preparation, showed reduced anxiety levels. Furthermore, Mayo Clinic notes that Valerian Root is one of the various supplements that might alleviate mild to moderate anxiety.

When it comes to sleep quality, Salvemini et al., (2015) revealed through a systematic review that Valerian might improve the sleep quality for patients with Parkinson’s disease. Thus, Valerian Root may represent an effective, gentler alternative to strong prescription medications for some patients dealing with anxiety and sleep disorders.